TST Best Bets- January 4, 2026

The final week of the NFL regular season has arrived. For some teams, Week 18 is about survival — win and you’re in. For others, it’s about seeding, rest and positioning for the road ahead. And for a select few, the focus has already shifted toward the future, where every snap carries draft implications just as meaningful as a playoff berth. Here are tonight’s best bets brought to you by BetOnline.ag. Click here to join. All new players get a 50% welcome bonus and up to $250 in free bets.

First Pick: Chargers +14

Rundown: The Los Angeles Chargers (11-5) head to the Mile High City for a divisional showdown against the Denver Broncos (13-3) to close out the regular season.

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Los Angeles enters Week 18 locked into a wild-card berth after a 20-16 loss to Houston in the regular-season home finale. With the division out of reach, head coach Jim Harbaugh has elected to rest quarterback Justin Herbert, paving the way for former first-round pick Trey Lance to get the start under center. While their postseason ticket is secured, seeding remains very much in flux, with all three wild-card spots still on the table depending on results around the league. The Chargers will look to complete a divisional sweep, but they’ll have to do so without their franchise quarterback leading the offense.

As for the Broncos, a win would clinch the No. 1 seed in the AFC, ensuring the road to the Super Bowl runs through Denver. The Broncos have been one of the league’s hottest teams, winning 12 of their last 13 games to secure their first division title since 2015 — a season that culminated in a Super Bowl victory. Despite owning the AFC’s best record, Denver has been inconsistent against the spread, covering just six of 16 games this season. Second-year quarterback Bo Nix has led the offense, tossing 25 touchdowns and 11 interceptions in 16 starts. Their fourth-ranked defense has been anchored by Nik Bonitto, who has compiled 13 tackles for loss and 12.5 sacks this season. Denver will look to avenge its Week 3 loss at SoFi Stadium while cementing home-field advantage throughout the playoffs.

Despite resting key starters, expect Los Angeles to keep it close and do enough to cover the 14-point spread in a hard-fought divisional matchup.

Second Pick: Rams -14.5

Rundown: The Los Angeles Rams (11-5) host the Arizona Cardinals (3-13) in a Week 18 NFC West matchup at SoFi Stadium.

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Los Angeles enters the regular-season finale looking to regain momentum ahead of the playoffs after back-to-back losses to Seattle and Atlanta ended its hopes of capturing the division crown. With San Francisco falling to Seattle on Saturday, a Rams win would lock up the No. 5 seed in the NFC and set up a Wild Card matchup against either the Carolina Panthers or Tampa Bay Buccaneers. A loss, however, would lock Los Angeles into the No. 6 seed and send them to either Philadelphia or Chicago in the opening round. Head coach Sean McVay confirmed earlier in the week that starters will be a full go. The Rams’ second-ranked scoring offense has been a driving force behind their success against the spread, covering in 11 of 16 games this season.

Arizona, meanwhile, limps into the finale after a disastrous campaign that unraveled following a 2-0 start. The Cardinals have dropped 13 of their last 14 games and will close the season with Jacoby Brissett under center as Jonathan Gannon’s squad turns its focus toward 2026. Despite the struggles, Arizona has been slightly more competitive at the betting window, posting a 6-10 record against the spread.

Anticipate MVP candidate Matthew Stafford to bounce back from a three-interception outing on Monday Night Football and lead Los Angeles to a convincing home victory to close out the regular season.