NFL experts predict winner of Colts vs. Texans Week 18 rematch

The Indianapolis Colts wrap up the 2025 NFL season on the road against the Houston Texans.

The first time around, the Texans would win this matchup 20-16 in Indianapolis.

So who do the NFL experts have winning this AFC South rematch?

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With the Colts out of playoff contention, Riley Leonard will get the start at quarterback this week. His backup, potentially, is Seth Henigan, who was recently signed to the practice squad.

That leaves Phillip Rivers as the team's third emergency quarterback. Anthony Richardson will remain on injured reserve.

The Texans will enter this game having won eight in a row and still in the mix for the division title.

In his first NFL start, Leonard will be up against one of the stingiest and most disruptive defenses in football.

To see how the Colts compare with the Texans, and who has the advantage where, you can find that info here.

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ESPN

A clean sweep. All five of ESPN's predictors are picking the Texans to win.

Sports Illustrated

Another sweep for the Texans, which I think will be common this week. The six Monday Morning Quarterback members are picking Houston.

Pro Football Talk

Mike Florio is picking the Texans to win 27-9. Chris Simms is taking Houston by a score of 27-13.

CBS Sports

Pete Prisco is taking the Texans 30-13 in this game.

"The Texans can still win the AFC South with a victory and a loss by the Jaguars. The Colts are done, which is why they are starting rookie Riley Leonard. He will be overwhelmed by that Texans defense. This will be ugly. Texans big."

This article originally appeared on Colts Wire: Colts vs. Texans: NFL experts pick winner of Week 18 AFC South matchup